The Horizon 2020 PEPPER project has held its second project meeting in Girona, Spain, three months after it was launched in Oxford in February 2016. The meeting took place from 5-6 May at the Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta and was attended by sixteen participants representing the six partner institutions in the consortium. Partners were pleased to celebrate the successful completion of the first milestone, which was the gathering of requirements for each of the components for the distributed development of this intelligent adaptive decision support system. User needs have been gathered from patients, clinicians and carers who will be involved at every stage of this patient-centric development. The next step is the research and development of the first prototype system which will be iteratively refined during a prolonged feasibility study prior to clinical trials.